美国德克萨斯休斯顿卫理公会研究所博士后职位

　　招聘简介：

　　外科博士后研究员：胃肠癌免疫学和纳米医学，美国德克萨斯州休斯顿

　　在休斯顿卫理公会研究所的Ashley M. Holder医学博士的实验室，可以立即获得外科学博士后研究员的职位，利用动物模型研究胃肠癌免疫学，研究创新的纳米粒子平台，为这些癌症开发转化治疗。休斯敦，德克萨斯州。我们正在专门研究利用高温和腹腔内（腹腔内）化疗（HIPEC）治疗起源或扩散到腹腔的癌症的手术技术的免疫效果。我们的实验室是一个多学科研究组织的一部分，致力于开发纳米粒子解决方案，以克服生物屏障和改善药物输送。这一职位为持续的科学发展和为具有高度转化影响的开创性研究做出贡献提供了极好的机会。我们是一个合作团体，在休斯敦，德克萨斯州，美国和全球范围内开展合作。

　　英文原文：

　　Postdoctoral Fellow in Surgery: Gastrointestinal Cancer Immunology and Nanomedicine, Houston, Texas, USA

　　A postdoctoral fellowship position in the Department of Surgery to study gastrointestinal cancer immunology utilizing animal models and investigate innovative nanoparticle platforms to develop translational treatments for these cancers is immediately available in the laboratory of Ashley M. Holder, MD, at the Houston Methodist Research Institute, Houston, Texas. We are specifically investigating the immunologic effects of a surgical technique that utilizes hyperthermia and intraperitoneal (intra-abdominal) chemotherapy (HIPEC) to treat cancers that originate or spread to the abdominal cavity. Our lab is part of a multidisciplinary research organization focused on developing nanoparticle solutions to overcome biologic barriers and improve drug delivery. This position provides outstanding opportunities for continued scientific development and for contributing to groundbreaking research with high translational impact. We are a collegial group with collaborations within Houston, Texas, the USA and around the globe. Our department’s research can be explored at: http://www.houstonmethodist.org/for-health-professionals/department-programs/nanomedicine/research/.

　　Requirements: MD or PhD with minimum 1 year of postdoctoral fellowship experience

　　Job Responsibilities:

　　• Plans, directs and coordinates complex research experiments following general technical procedures, under the guidance of the PI.

　　• Works with PI to formulate research plans, coordinates project activities and establishes appropriate reporting procedures.

　　• Analyze the data generated from these experiments and provide high level analysis to PI.

　　• Prepares manuscripts, meeting presentations, and performs background literature searches.

　　• Makes modifications to research procedures in collaboration with the PI.

　　• Confers with PI regarding results obtained and receives suggestions for modification to procedures and/or interpretation of final data.

　　• Provide assistance and oversight of staff, and graduate students ensure projects are being completed according to the research plan.

　　• Perform/supervise rodent surgery including laparotomy, intraperitoneal injections, and IVIS, while also maintaining an accurate animal database.

　　• Lab work will also involve tissue culture; DNA, RNA, and protein-related assays; drug-sensitivity assays.

　　• Studies will also interface with experts in immunology, nanomedicine, pathology, biostatistics, medicinal chemistry and other specialties.

　　• Assist PI in overseeing general lab operations including inventory, lab organization and maintain certain equipment/facilities. Must demonstrate compliance with policies, procedures and regulations of the Animal Resource Center, IACUC, Animal Welfare Act, Public Health Service Policy, AAALAC guidelines and other applicable regulatory guidelines for which essential training will be provided.

　　• Will involve travel to meetings or conferences if secured travel funding.

　　• Must be willing to adjust working hours according to the nature of ongoing experiments and many times work extended hours to finish the experiments. Working on weekends and holidays are required depending on the ongoing experiments and need to accelerate data generation and data collections.

　　Required Skills:

　　Ÿ Ability to work well with others and to work independently. The individual should be able to follow directions and protocols.

　　Ÿ Ability to collect and analyze data with attention to detail and do multiple tasks simultaneously.

　　Ÿ Effective oral and written communication skills. Must be able to effectively communicate with the PI/supervisor as well as other lab members.

　　Ÿ Good interpersonal skills; ability to work and communicate with various individuals within and external to the Research Institute.

　　Ÿ Good organization skills; ability to multi-task, prioritize and meet deadlines. Must demonstrate attention to detail and accuracy and follow-through on assigned tasks.

　　Ÿ Ability to work effectively independently and collaboratively within a team.

　　Ÿ Ability to work with sensitive information and maintain confidentiality.

　　Ÿ Good problem-solving skills; must demonstrate good analytical skills, sound judgment and good decision-making.

　　Ÿ Ability to rely on and follow instructions and pre-established guidelines to perform the functions of the job.

　　Ÿ Ability to operate laboratory equipment and learn to operate new instruments

　　Ÿ Familiarity with policies and procedures of lab and chemical safety

　　Ÿ Knowledge in Microsoft Office, database applications, and with internet navigation.

　　Ÿ Willingness to learn new techniques, procedures, processes, and software programs as needed.

　　Houston is one of the most diverse cities in the country with a low cost of living and fantastic neighborhoods, schools, and activities from sports to culture to outdoor recreation.

　　Please send your CV, a letter of interest, and names/contact information for three references to:

　　Ashley M. Holder, MD

　　Assistant Professor of Surgery in Nanomedicine

　　Houston Methodist Research Institute

　　6670 Bertner, R8-216

　　Houston, TX 77030

　　amholder@houstonmethodist.org