英国剑桥大学病毒学博士后职位

2023年07月25日

来源：知识人网整理

摘要：

英国剑桥大学病毒学博士后职位

剑桥大学（英文：University of Cambridge；勋衔：Cantab），坐落于英国剑桥郡，是一所公立研究型大学，采用传统学院制。学校是罗素大学集团成员，全球大学校长论坛成员，被誉为“金三角名校”、“Doxbridge”、“G5”。

剑桥大学是英语世界中第二古老的大学，前身是一个于1209年成立的学者协会。剑桥大学是英国罗素大学集团、全球大学高研院联盟、金三角名校、国际应用科技开发协作网及剑桥大学医疗伙伴联盟成员，衍育了科技聚集地“硅沼（Silicon Fen）”。设八座文理博物馆，馆藏逾1500万册的图书馆系统及全球最古老的出版社——剑桥大学出版社。

Post-doctoral Scientist in Virology (Fixed Term)

University of Cambridge

Post-doctoral Scientist in Virology (Fixed Term)

We wish to recruit a highly motivated Postdoctoral Research Scientist to join the laboratory of Dr Colin Crump within the Division of Virology at the Department of Pathology, University of Cambridge (https: // www. path.cam.ac.uk/research/virology-division/crump-group).

Herpesviruses are ubiquitous viral pathogens that establish life-long latent infections within their hosts, with periodic reactivation events that lead to shedding of infectious viruses and spread to new hosts. Herpesviruses are associated with many serious diseases in humans and animals including life- threating conditions in people with weakened immune systems. The laboratory uses a broad range of molecular and cellular virology approaches to understand how viruses interact with, modify, and antagonise cellular machinery to evade antiviral mechanisms and promote virus replication and spread.

We have recently discovered a novel viral protein complex expressed by herpes simplex virus 1 (HSV-1) that targets many host proteins for degradation, particularly cellular factors involved in antiviral responses within the nucleus. This research will investigate the molecular mechanisms by which this viral protein complex remodels the cellular proteome to promote herpesvirus infection. You will contribute to advancing the fundamental understanding of virus-host interactions, antiviral pathways, and mechanisms by which viruses antagonise intracellular cellular defences.

The successful applicant will join a collaborative and inclusive team of researchers within the Division of Virology laboratories on the Cambridge Biomedical Campus, the largest center of medical research and health science in Europe. You will have access to state-of-the-art facilities and gain experience of cutting-edge experimental approaches in molecular and cellular virology including advanced microscopy, protein-protein interaction screens, quantitative mass spectrometry, next generation sequencing, CRISPR/Cas9 genetic engineering and working with iPSC cell lines. The successful applicant will benefit from the dynamic, collaborative, and supportive environment of the laboratory, the Virology Division, the wider Department of Pathology and the large infection and immunity research community across Cambridge. The project will also benefit from close collaboration with the groups of Prof. Stephen Graham and Prof. Mike Weekes within Cambridge, and Dr Anna Cliffe at University of Virginia, bringing together leading scientific and technical expertise in cell biology, structural virology, advanced proteomics, and herpesvirus latency. Due to the supportive nature of the laboratory enthusiastic candidates will have the opportunity to learn additional techniques and expand their research skills. Furthermore, we encourage creative thinking when tackling scientific problems and are keen for lab members to adopt new technologies and approaches when appropriate. This project will provide the opportunity for research visits to University of Virginia, USA.

The ideal candidate will be highly motivated, independent, and enthusiastic, with a track record of successful research in virology, cell biology, immunology, or a related field, commensurate with career stage. Experience with working at containment level 2, cellular and molecular virology techniques, fluorescence microscopy, or proteomics are desirable. Strong analytical and problem-solving skills, written and verbal communication skills, and the ability to work independently as well as part of a team and a willingness to learn new skills are essential.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

Applications are welcome from internal candidates who would like to apply for the role on the basis of a secondment from their current role in the University.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

For informal enquiries, please email cmc56@cam.ac.uk

Please quote reference PK37405 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Department/Location

Department of Pathology, Cambridge

Salary

£35,308-£43,155

Reference

PK37405