美国希望之城博士后职位—淋巴瘤研究

美国希望之城博士后职位—淋巴瘤研究

希望之城国家医疗中心(City of Hope NationalMedical Center)是一所顶尖的美国非盈利研究和治疗中心，专注于癌症、糖尿病和其他危及生命的疾病。

Postdoctoral Fellow - Lymphoma Research - Alexey Danilov Lab

City of Hope

Position Summary

Dr. Alexey Danilov’s research is focused on the mechanisms of lymphomagenesis and identification of novel therapeutic targets in B-cell lymphoma and other cancers. Following our recent laboratory discoveries, we also explore the immunomodulatory effects of novel targeted agents and aim to harness their potential to enhance the efficacy of immunotherapy and novel cellular therapies.

We are looking for a Postdoc to advance one of the following areas of interest in our laboratory:

·         immunomodulatory effects of targeted agents and mechanism-driven approaches to enhance efficacy of immune and cellular therapies.

·         oncogenic mechanisms of transcriptional cyclin-dependent kinases.

Dr. Danilov's group coordinates a number of Phase I/II clinical trials, thus presenting an opportunity to verify the pre-clinical hypotheses in the clinical setting and conferring immediate relevance to pre-clinical investigations.

This position is created to continue research studies currently funded by the NCI R01, the Leukemia and Lymphoma Society Translational Research Program Award, MCL Research Initiative and Scholar Award. The project will match the candidate’s interests and experience.

Highly motivated candidates with expertise in molecular biology, immunology, biochemistry and in vivo models who are interested in a career in oncology basic/translational research will be most competitive for this position.

The individual will be responsible for leading a collaborative research project focused on extrinsic mechanisms and drug resistance. Expertise with molecular biology and in vivo models will be required for this project. Additional responsibilities include but are not limited to: maintaining a high level of professional expertise in the field; supervising and providing guidance and mentorship to other researchers within the laboratory; designing and directing or executing experiments; and establishing laboratory procedures and systems that enforce and maintain a high level of organization in the lab. The individual should have demonstrated success in leading, managing and participating in collaborative projects and a distinguished record of scientific and technical accomplishments.

Basic education, experience and skills required for consideration:

The individual will have at least 3 years of post-graduate research experience in the relevant field. They are likely to have deep expertise in a singular area of focus but may also have worked as boundary spanners across multiple fields. Achieving this position requires that the researcher has demonstrated a satisfactory track record of scholarly activity including high-quality peer-reviewed publications. In order to maintain successful track record and show potential of growth, the individual must be actively engaged in publishing high-quality manuscripts, the development and submission of grant/funding proposals and leading projects that are aligned with the lab’s focus area.

·         Doctoral degree in relevant field and 3-5 years of relevant post-doctoral work experience. Fiveormoreyearsin aresearchposition,includingatleast 4yearsofsupervisoryandprojectmanagementexperience.

·         Expertise in cancer biology, molecular/hematopoiesis, and genomics required. Experience with murine leukemia, hematopoiesis, and in FACS based methods, biochemistry, and molecular biology strongly preferred.

·         Proficient with computers specifically MS Office (which includes, Excel, Access, Word, and PowerPoint) and statistical analysis software.

·         Strong publication record.

·         Experience handling chemical and biologically hazardous materials.

·         Knowledge of policy and regulations applicable to the laboratory, including but not limited to safety, animal, and radiation.

·         Technical proficiency, scientific creativity collaborative ability, and independent thinker.

·         Experience with drug sensitivity/synergy analyses preferred.

Additional information:

·         For consideration, please email your resume to Dr. Alexey Danilov at adanilov@coh.org

·         For more information about Dr. Danilov’s lab, please visit here.

·         Pay Rate: $31-$34.23

·         The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.

·         As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

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