美国希望之城博士后职位---DNA代谢在癌症、衰老和免疫中的作用

美国希望之城博士后职位---DNA代谢在癌症、衰老和免疫中的作用

希望之城国家医疗中心(City of Hope NationalMedical Center)是一所顶尖的美国非盈利研究和治疗中心，专注于癌症、糖尿病和其他危及生命的疾病。

该医疗中心是美国国立癌症研究院（National Cancer Institution）指定的53所癌症综合中心之一，也是美国国立综合癌症网络的创立会员和中央数据协调中心。被权威新闻杂志周刊《美国新闻与世界报道》(U.S News & World Report)列为全美最佳癌症医院第七名和“美国最佳癌症和泌尿科医院”之一。

Postdoctoral Fellow - DNA Metabolism in Cancer, Aging & Immunity

City of Hope

Job Description

Postdoctoral positions are now available in the laboratory of Dr. Yilun Liu at the Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope. Dr. Liu’s research topics include:

·     Dissecting the molecular mechanism by which transcription-associated genomic instability and epigenetic deregulation contribute to developmental abnormalities and cancer.

·     Developing pharmaceutical mechanisms for cancer therapy by targeting enzymes important for preventing the formation of DNA breaks arose during accelerated cell growth such as in cancer cells as well as factors important for the BRCA2 and PARP-dependent repair pathways to keep these DNA breaks unrepaired.

·     Exploring the role of mitochondrial DNA in cancer pathogenesis and in immune response.

·     Targeting SUMOylation of topoisomerase I in chemo- and immuno-therapies.

Basic education, experience and skills required for consideration:

·     A Ph.D. degree in life or biomedical sciences, or a related discipline is required.

·     Experience in biochemistry and/or cell biology is preferred.

Additional information:

·     Dr. Liu’s research is currently supported by NIH R01 grants from National Cancer Institute (NCI) and National Institute of General Medical Science (NIGMS) and a grant from Pancreatic Cancer Action Network.

·     Dr. Liu’s group has published in journals, including Nature Communications, Cell Reports, EMBO Journal and PNAS. A full list of publications can be foundat

·     My Bibliography or Google Scholar.

·     For more information on Dr. Liu’s research please visit,here.

·     The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.

·     As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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Salary / Pay Rate Information:

Pay Rate: $31.00 - $34.23 / hour

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