瑞士伯尔尼大学博士后—心脏发育和再生的遗传与表观遗传调控

瑞士伯尔尼大学博士后—心脏发育和再生的遗传与表观遗传调控

伯尔尼大学（德文：Universität Bern；英文：University of Bern，简称UniBe）坐落于瑞士首都伯尔尼，是世界上著名的研究型大学。该校创建历史可以追溯到16世纪早期宗教改革中建立的清教神学院。学校在建校时即拥有3位教授，到十七世纪末拥有6位教授，到十八世纪伯尔尼大学在人文和神学领域一直处于统治地位。包括埃米尔·特奥多尔·科赫尔和库尔特·维特里希在内的诺贝尔奖得主都曾在此学习工作。

Junior Postdoctoral researcher Genetic and epigenetic regulation of heart development and regeneration

University of Bern

Junior Postdoctoral researcher

Genetic and epigenetic regulation of heart development and regeneration 100%

The group of Nadia Mercader studies the cellular and molecular mechanisms of heart development and regeneration. Using the zebrafish model and combining genetic manipulations with omic approaches, we investigate how cardiomyocyte proliferation is influenced by different cell types including fibroblasts and macrophages and how cardiac precursor cells acquire cell fate identity during development. We are also interested in studying the mechanisms of epigenetic inheritance caused by cardiac injury across generations.

The group is located at the Institute of Anatomy, within the Medical faculty of the University of Bern. It is also embedded into the Cardiovascular Research Cluster that includes several groups working at the University of Bern and University Hospital Inselspital. The Mercader group also has an affiliation to the Centro Nacional de InvestigacionesCardiovasculares CNIC.

Tasks

The candidate will work on a research project in the frame of the ERC Consolidator Grant TransReg 81971 and will also be involved in further research projects in the group by providing support with bioinformatics analysis such us

scRNA-seq, small RNA-seq and spatial transcriptomics.

ATAC-seq, Cut&Run, CHIP-seq analysis.

Requirements

Academic Degree: PhD (obtained 2019 or later, but if justified also earlier time-points are accepted)

Training in bioinformatics, good knowledge in programming languages R and Python, previous experience in transcriptomics analysis

Background in life sciences and interest in biological questions.

Previous experience with zebrafish omic approaches will be a plus

Fluent in English including good scientific writing skills, knowledge in German will be a plus

We offer

A postdoctoral Researcher position with a competitive salary for 2 years with options of extension. Starting date February 2023 or upon agreement.

A stimulating, cooperative, and supportive environment and close collaboration with international research teams.

Multiple opportunities for continuous education.

The University of Bern is an equal opportunity employer and welcomes all individuals who will contribute to the diversity and excellence of the institution. The University of Bern is committed to support young researchers and offers Initiator Grants and coaching programs among others for postdoctoral fellows.

Please send your CV including a list of publications and scientific achievements, statement of experience, letter of motivation and contact information of two references to Prof. Nadia Mercader.

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