英国牛津大学博士后职位---多巴胺和星形胶质细胞生物学在健康和帕金森病中的作用

英国牛津大学博士后职位---多巴胺和星形胶质细胞生物学在健康和帕金森病中的作用

Post-doctoral Research Scientist in dopamine and astrocyte biology in health and Parkinson's disease

University of Oxford

Description

The Cragg Group at the University of Oxford are conducting an MRC-funded research project to explore the role of astrocytes in the regulation of striatal dopamine function in health and parkinsonism. We are now seeking to appoint a Postdoctoral Research Scientist with an interest in astrocyte biology to join the group and work as part of this exciting project.

The successful candidate will develop, conduct, analyse and report on studies to elucidate dopamine transmission, its regulation and dysregulation by activity in astrocytes, related circuits and signalling molecules in mouse brain. The technical approaches involved will include detection of dopamine neurotransmission using fast-scan cyclic voltammetry, imaging of genetically encoded fluorescent neurotransmitter reporters, and/or whole cell electrophysiology, in brain slices in mouse models of Parkinson's disease. The candidate will also collaborate on projects with the Cragg Group's internal and external partners and when appropriate, undertake the training and supervision of other members of the Group. The candidate will be responsible for acquiring, analysing and interpreting scientific data, ensuring that the data are of the highest quality.

In addition to having, or nearing completion of, a PhD/M.D. or equivalent qualification in a relevant discipline, candidates should have a promising track record of original research in their particular field of neuroscience. Candidates are also expected to have technical expertise in real-time electrochemical or electrophysiology recordings in brain slices, in neurosurgery, with rodents and to provide evidence of creative and critical thinking as applied to the delivery of a focused programme of research. Experience of studying astrocytes is desirable.

The post holder will work in the Group led by Professor Stephanie Cragg, and will be based at the Department of Physiology, Anatomy and Genetics, Sherrington Building, Parks Road, Oxford, OX1 3PT.

This is a full-time, fixed-term post available until 18 April 2024 funded by the MRC. Owing to the nature of this position, any offer of employment with the University will be subject to a satisfactory security screening.

Informal enquiries can be addressed to Stephanie.cragg@dpag.ox.ac.uk.

Closing date for applications is noon on Monday June 6th

Interviews are likely to be held between June 17th and 24th