美国哈佛医学院波士顿儿童医院干细胞研究博士后职位

美国哈佛医学院波士顿儿童医院干细胞研究博士后职位

Postdoctoral Fellow

Boston Children's Hospital

Location: Boston, MA

Job Number: 7075737

Posting Date: Mar 5, 2021

Application Deadline: Open Until Filled

Job Description

Laboratory:

Melero-Martin Lab

Juan Melero-Martin, PhD

Boston Children’s Hospital

Harvard Medical School

Harvard Stem Cell Institute

Boston MA, United States

Description

Positions for Postdoctoral Fellows are available in the laboratory of Dr. Juan Melero-Martin (meleromartinlab.com) at Boston Children’s Hospital and Harvard Medical School. The postdoctoral researchers will work on NIH-funded projects to study human pluripotent stem cells’ differentiation into tissue-specific vascular cells for use in regenerative medicine. The overarching goal of the lab is to develop novel approaches to vascularization and tissue regeneration. Work will involve human stem cell culture, molecular biology, and mouse xenograft models.

Background

Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA. Wang K, Lin RZ, Hong X, Ng AH, Lee CN, Neumeyer J, Wang G, Wang X, Ma M, Pu WT, Church GM, Melero-Martin JM. SciAdv 2020; 6, eaba7606

Bioengineering hemophilia A-specific microvascular grafts for delivery of full-length factor VIII into the bloodstream. Neumeyer J, Lin RZ, Wang K, Hong X, Hua T, Croteau SE, Neufeld EJ, Melero-Martin JM. Blood Adv 2019; 3(24):4166-4176

Requirements

       Ph.D., ScD, or equivalent degree

       A record of innovative publications

       Demonstrated skills in stem cells

       Excellent communication and organizational skills

       Experience with cell culture and animal models

       Strong interest in regenerative medicine