美国迈阿密大学眼科学博士后职位招聘

　　招聘简介：

　　博士后助理（2个职位-眼科）

　　·迈阿密大学

　　·地点：佛罗里达州迈阿密

　　·工作编号：7056325（参考号：R100030289）

　　·发布日期：2019年3月6日

　　·申请截止日期：开放至填写

　　职位描述

　　迈阿密大学米勒医学院巴斯科姆-帕尔默眼科研究所正在寻找两名积极进取的博士后，他们在分子/细胞生物学和动物研究方面具有丰富的研究经验，有助于发现和开发生物药物。这些职位是美国国家卫生研究院资助的新药物治疗项目的一部分。

　　英文原文：​

　　Postdoctoral Associate (2 Positions - Ophthalmology)

　　·         University of Miami

　　·         Location: Miami, FL

　　·         Job Number: 7056325 (Ref #: R100030289)

　　·         Posting Date: Mar 6, 2019

　　·         Application Deadline: Open Until Filled

　　Job Description

　　The Bascom-Palmer Eye Institute at the University of Miami, Miller School of Medicine, is searching for two highly-motivated Postdoctoral Associates with strong research experience in molecular/cellular biology and animal research for biological drug discovery and development. These positions are part of a new NIH-funded project to develop novel drug therapies.

　　Research will focus on developing next-generation targeted anti-angiogenic therapies for various vascular diseases. The laboratory recently developed the only technology of ligandomics with broad applicability to discover high-quality drug targets for novel therapies of different diseases, including but not limited to angiogenic diseases (PMID: 29326083). Using this powerful technology, we discovered highly promising drugs target and developed next-generation targeted anti-angiogenic therapies (PMID: 28330905). This project will investigate drug candidates in various stages. These include characterization of humanized antibodies to treat angiogenic diseases in animal models, analysis of other newly-identified novel drug targets in vitro and in vivo, and ligandomics screening to discover additional unknown drug targets. Our research activities are described at https://umiamihealth.org/bascom-palmer-eye-institute/research/meet-our-researchers/wei-li-phd. Our recent publications can be found at http://www.ncbi.nlm.nih.gov/sites/myncbi/wei.li.2/bibliography/40172985/public/?sort=date&direction=descending.

　　The research activities are to: 1) characterize molecular mechanisms of a novel angiogenic factor in vitro and in vivo; 2) investigate the therapeutic efficacy of a novel anti-angiogenic therapy to treat retinal vascular diseases, including retinopathy of prematurity, diabetic retinopathy, and wet age-related macular degeneration (AMD) angiogenesis in animal models; 3) analyze the toxicology and pharmacokinetics of the new therapy in animal models; 4) ligandomics analysis; and 5) write postdoctoral fellowships. After initial training, Postdoctoral Associates will independently investigate the mechanistic studies in vitro and analyze preclinical therapeutic efficacy and toxicology studies in animal models.

　　Minimum Qualifications

　　Candidates must have a Ph.D. and/or MD, have productive scientific contributions through publication of high impact peer-reviewed papers, and show strong commitment to science. Applicants with advanced skills in molecular biology, cell biology, protein biochemistry, immunohistochemistry and animal research are highly desired. Experience in bioinformatics analysis is a plus. Excellent verbal and written communication skills are required. These positions represents an excellent opportunity for career development in drug discovery and development with opportunities to interact with our industrial partners.

　　Bascom Palmer Eye Institute has been ranked as the #1 eye hospital in the past 15 consecutive years (2004 -2017) by U.S. News and World Report.

　　If interested, please send a CV, 1-2 page summary/Cover letter describing past accomplishments and 3 references, including contact information to Dr. Wei Li at w.li@med.miami.edu. and complete an online employment application by applying to this job. Positions are available immediately.

　　UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.

　　Patient safety is a top priority. As a result, during the Influenza ("the flu") season (September through April), the University of Miami School of Medicine requires all employees who provide ongoing services to patients, work in a location (all Hospitals and clinics) where patient care is provided, or work in patient care or clinical care areas, to have an annual influenza vaccination. Failure to meet this requirement will result in rescinding or termination of employment.