美国迈阿密大学阿茨海默病与基因组学研究博士后职位招聘

　　招聘简介：

　　博士后助理（2个职位-阿尔茨海默病和基因组学研究）

　　·迈阿密大学

　　·地点：佛罗里达州迈阿密

　　·工作编号：7056324（参考号：R100030341）

　　·发布日期：2019年3月6日

　　·申请截止日期：开放至填写

　　职位描述

　　博士后职位——阿尔茨海默病和基因组学——迈阿密大学米勒医学院人类基因组学约翰·P·胡斯曼研究所。

　　迈阿密大学米勒医学院的Hussman人类基因组学研究所是阿尔茨海默病（AD）和其他神经退行性疾病研究的领先中心。HIHG的研究人员对来自不同种族和种族背景的患者进行了大量的遗传研究，以了解复杂疾病的遗传基础。目前正在进行的努力是为了了解特定基因和基因变异对AD疾病病理学的影响。该研究采用了新的功能基因组学和疾病建模方法，目的是弥合基因组学和药物发现之间的差距。其他职责包括参与项目规划、赠款和手稿撰写，以及指导更多的实验室初级成员。该项目的主要研究者是Jeffery M Vance博士和Derek Dykxhourn博士。

　　英文原文：​

　　Postdoctoral Associate (2 Positions - Alzheimer and Genomics Research)

　　·         University of Miami

　　·         Location: Miami, FL

　　·         Job Number: 7056324 (Ref #: R100030341)

　　·         Posting Date: Mar 6, 2019

　　·         Application Deadline: Open Until Filled

　　Job Description

　　Postdoctoral positions – Alzheimer Disease and Genomics – John P. Hussman Institute for Human Genomics at the University of Miami, Miller School of Medicine.

　　The Hussman Institute for Human Genomics (HIHG) at the University of Miami, Miller School of Medicine is a leading center for the study of Alzheimer disease (AD) and other neurodegenerative disorders. Investigators at the HIHG have conducted numerous genetic studies in patients from diverse ethnic and racial backgrounds to understand the genetic underpinnings of complex disorders. Ongoing efforts are under way to understand the impact that specific genes and genetic variants have on AD disease pathology. The research uses novel functional genomics and disease modeling approaches with the goal of bridging the gap between genomics and drug discovery. Other duties will include participating in project planning, grant and manuscript writing, and the mentoring of more junior members of the laboratory. Lead investigators for this project are Dr. Jeffery M Vance MD, PhD and Dr. Derek Dykxhoorn, PhD.

　　Minimum Qualifications

　　We are looking for outstanding scientists with laboratory experience holding a PhD, MD or equivalent degree in the fields of Genetics, Functional Genomics, Molecular Biology, Stem Cell Biology or related disciplines to join our laboratory as part of a project to identify the factors that modify the risk to develop AD in ApoE4 carriers of different ethnicities. Candidates should be independent and highly motivated with strong communication and critical thinking skills, as well as a dedication to teamwork and collaboration. Candidates will utilize epigenetic, iPSC technology and CRISPR genome editing, as such, experience in these technologies is desirable although not required.

　　UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.

　　Patient safety is a top priority. As a result, during the Influenza ("the flu") season (September through April), the University of Miami School of Medicine requires all employees who provide ongoing services to patients, work in a location (all Hospitals and clinics) where patient care is provided, or work in patient care or clinical care areas, to have an annual influenza vaccination. Failure to meet this requirement will result in rescinding or termination of employment.