美国华盛顿大学圣路易精神病学博士后职位

　　Post Doc Instructions

　　Please do not submit an application to this posting. To apply for this postdoctoral research opportunity, follow the directions below in “Applicant Special Instructions”.

　　Job Type/Schedule

　　This position is full-time and works approximately 40 hours per week. This position is offered initially up to 1-2 years with a maximum of 5 years.

　　Department Name/Job Location

　　This position is in the Department of Psychiatry. This position is for the Medical School Campus.

　　Essential Functions

　　A postdoctoral research fellow position is available immediately in the Cruchaga Lab at Washington University School of Medicine. Washington University School of Medicine is ranked among the top ten medical schools in the country and is a thrilling learning environment for postdocs. The Cruchaga Lab is part of the Hope Center for Neurological Disorders which fosters knowledge, sharing, and collaboration among many different research groups that study a range of nervous system diseases with the common feature of neurodegeneration or death of nerve cells.

　　Our team is focused in understanding the biology of Alzheimer Disease, Parkinson disease and other neurodegerative diseases by combining genetics and functional genomic approaches. Recent studies from our lab and others have identified novel genes associated with AD, such asTREM2, PLD3, CPAMD8 and ABCA7, among others. We aim to explore the role of these genes in the pathogenesis of Alzheimer disease using a variety of cell systems from both animal models and human lines, including immortalized, primary, and iPSC lines. We are an enthusiastic team and offer intensive training and mentoring. The successful candidate will join an interdisciplinary team and will be expected to perform functional analysis of the candidate genes, in collaboration with other teams with expertise in iPSC and animal models. The position is initially restricted to the evaluation of a defined set of candidate genes, but there are many opportunities to initiate projects that contribute to our understanding of the molecular and cellular mechanisms underlying Alzheimer disease. It is expected that the selected applicant will be involved in the design and execution of experiments to tackle the project objectives, general tasks related to the lab work routine, active participation in periodic laboratory meetings, manuscript preparation and publishing, and the presentation of work in international conferences.

　　Required Qualifications

　　PhD in cell biology, biochemistry, or related areas, ideally with a focus on neuroscience or related human field.

　　Preferred Qualifications

　　Expertise in cell culture, Western blot, ELISA, site-directed mutagenesis, PCR, and qPCR, among others.

　　Knowledge of genome editing techniques and iPSC cultures is desirable.

　　Demonstrated ability to implement laboratory procedures, conduct research and records findings.

　　Salary Range

　　Base pay commensurate with experience.

　　Benefits

　　This position is eligible for full-time benefits. Please visit our website at http://hr.wustl.edu to view a summary of benefits.

　　Applicant Special Instructions

　　Applicants should email a curriculum vitae and statement of research interests along with contact information for three references to Dr. Carlos Cruchaga (cruchagac@wustl.edu). Evaluation of applications will begin immediately.

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