美国全国儿童医院研究所疫苗和免疫中心肝炎病毒的生命周期和发病机制博士后职位

The Center for Vaccines and Immunity at the Research Institute at Nationwide Children’s Hospital (Columbus, OH) has a post-doc position available to study the hepatitis virus life cycle and pathogenesis. Previous studies by the PI have shown that the hepatitis A virus (traditionally thought to be nonenveloped) hijacks host membranes to evade antibody response and facilitate its spread (Nature. 496: 367-71). A similar phenomenon exists for the hepatitis E virus (Trends Microbiol. 22: 59-64). These novel “quasi-enveloped” viruses create a new paradigm in virus-host interactions. Projects will focus on understanding how the quasi-envelopment affects virus spread and the control of these infections. Opportunities also exist to work on the hepatitis B virus.


Responsibilities: The successful candidate is expected to have excellent technical and communication skills, perform self-directed research, and assist the PI in preparing manuscripts and grant applications.


Minimum requirements: Candidates must have a PhD or equivalent with strong research experience in molecular biology, cell biology and/or immunology. Applicants with experience in virology or innate immunity are particularly encouraged to apply. Competitive salary will be commensurate with experience. Interested applicants should submit a CV, a brief description of their research achievements and interests, and a list of 3 references to Dr. Zongdi Feng (Zongdi.Feng@nationwidechildrens.org)