Postdoctoral Research Associate : Chapel Hill, NC, United States

Postdoctoral Positions of Gene Regulation, Epigenetics and/or Cancer Biology

Job Description 
Lineberger Cancer Center & the Department of Biochemistry
University of North Carolina at Chapel Hill (UNC) School of Medicine

Postdoctoral associate positions available for highly motivated candidates with a fresh PHD training in molecular biology, cell biology or biochemistry to join the Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill (UNC) School of Medicine, USA. The lab emphasizes on mechanistic understandings of gene regulation, chromatin, stem cells, and human disease, notably cancer (see our recent publications at Molecular Cell 2013, Blood 2015, Cell Reports 2015; Cancer Cell 2016).

Multiple on-going projects include (1) biochemical characterization of epigenetic factors/complexes that regulate gene expression in stem cells or cancer cells; (2) CRISPR/dCas9-based editing and screening of epigenetic pathways in gene expression; (3) knockout and knock-in mouse models with deficiency in histone methylation regulation in context of development and tumorigenesis, with a special focus on hematopoietic cancer and disease; (4) epigenomic and transcriptome analyses (ChIP-Seq and RNA-Seq) of normal versus cancer cells to delineate pathways essential for tumor growth.

Applicants should be self-motivated with a track record of publication in the above area, have laboratory and analytical skills, and be a critical thinker.