美国Fred Hutchinson癌症研究中心招聘儿童脑癌方向博士后
摘要：
Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer with minimal side effects. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first and largest cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
A Postdoctoral Research Fellow position as the Kellen Joyce Fellow is immediately available in the laboratory of James M. Olson (and collaboratively with Patrick Paddison) in the Clinical Research Division of the Fred Hutchinson Cancer Research Center (FHCRC). The fellow will join an ongoing NIH-funded program focused on dissecting the pathophysiology of pediatric brain cancers and developing therapeutic candidates. Working with the senior members of the team, the fellow will design and implement a research program to prioritize candidate therapeutic targets and interrogate therapeutic candidates using patient-derived xenografts and technology that enables multiplexed comparisons in vivo (Klinghoffer, Sci. Transl. Med. 2015 Apr 22;7(284). The ideal candidate will bring passion, a willingness to overcome challenges and intellectual aptitude to dissect potential therapeutic targets and the compensation mechanism lost as normal cells become cancerous. The successful applicant will be expected to leverage their own expertise and the resources available at the FHCRC to perform cutting edge scientific research. With the end goal of becoming a successful, independent researcher, they will engage with their colleagues to develop and execute on innovative approaches to the discovery of novel therapeutics with potential translation into the clinical setting. This position will require contribution both as an individual and as part of a larger team, as well as mentorship to junior lab members. The successful candidate may also have the opportunity to participate in the Optides/Project Violet program.
To be considered the successful candidate must have:
A PhD, MD or equivalent (or be nearing completion), ideally in the areas of pharmacology, biochemistry, molecular biology or related field
Strong publication record
Understanding of the pathophysiology of cancer and therapeutic discovery
Experience with assays amenable to drug discovery or pathway delineation
Experience with gene editing techniques (shRNA or CRISPR/Cas9) is strongly desired.
Please apply with a letter summarizing previous work experience, personal strengths and future interests, a resume, and contact information for three professional references. |
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| Contact: |
Fred Hutchinson Cancer Research Center
Seattle , WA
United States |
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