录取机构：美国国立卫生研究院(National Institutes of Health，NIH)
Postdoctoral Associate, Department of Anesthesiology Department: Department of Anesthesiology, Duke School of Medicine Job Description: An opportunity exists to join our research group in neuroinflammation and cognitive outcomes. We are interested in the mechanisms underlying postoperative neurocognitive disorders and strategies to modulate neuroinflammation and innate immunity. Presently we have active projects in: • neuromodulation of cholinergic signaling to treat postoperative neurocognitive disorders: mechanisms of action and design of innovative therapies • mechanisms and regulation of blood-brain barrier opening and microglial function after peripheral surgery: modeling, preclinical studies, and clinical studies • acute pain signaling and resolution of neuroinflmmation: mechanisms and innovations to increase therapeutic efficacy Requirements: We seek a highly-motivated individual who enjoys the freedom to pursue their own ideas in a supportive environment to join our team. A PhD degree is required with training in neuroscience, immunology, biochemistry, molecular biology, pharmacology, and/or a related field. Experience with mouse models, biochemistry/molecular biology, and immune-histology is required. The candidate will work in a strong interdisciplinary and collaborative environment at Duke University and Duke Medical Center.
PhD Project: 3D Printing of Fibre Reinforced Polymer Composites EmployerUniversity of Leeds LocationLeeds, United Kingdom Job Description Funded PhD project: Worldwide (International, UK and EU) Value: Funding covers the cost of fees and provides a maintenance of £14,553 for the 2017/18 academic year. Funding duration is 3 years. Number of awards: Funding for this award is not guaranteed. This research project is in competition for scholarship funding with other projects and will be awarded on a competitive basis. Project description 3D printing of Fibre Reinforced Polymer (FRP) composites is being under considerable research recently, but very few developed technologies being commercialized due to the existing limitations. There are still a lot of problems to solve in order to refine the printing processes and the printed FRP composite parts/products are severely constrained by little understanding of the technology from materials, to manufacturing process and to structures. Most 3D printing processes are also time-consuming and it is difficult to print large scale composite parts/products. New printing technologies that is scalable and fast should be developed in order to become adopted by the industry. The development of such new technologies rely on the integrated consideration of the properties of the printable materials (i.e. fibre and polymer), structural performance of the printed parts as well as the robustness and efficiency of the printing system. One of the main challenges is that the printed composites usually have lower mechanical strength than the composites manufactured by conventional moulding technologies, which in some cases may not meet their functional requirements. This is mainly due to the voids introduced in the composites during the printing and the addition of fibre (carbon or glass) could further increase the porosity due to defects in the fibre/matrix interfacial bonding. This project aims to use a particle methods based approach (a 2D integrated SPH-DEM approach has already been developed and needs to be extended to 3D) to model and optimize the 3D printing processes of FRP composites so as to reduce voids and improve fibre/matrix interfacial properties. Experimental testing and characterization of fibre, polymer and fibre/matrix interface will be carried out with results fed into the computational model. Existing printing processes (such as fused deposition method and direct write technique) will be modelled and optimal printing processes will be proposed. Based on the modelling and optimization, the project also has the potential to develop a new and innovative printing technique that can mitigate the limitations faced by the existing printing techniques, and on such occasion a small lab based printing device/prototype for composites will be developed.
Postdoctoral Associate EmployerBaylor College of Medicine LocationHouston, TX Application DeadlineOpen Until Filled Job Description Postdoctoral Associate needed to perform genetics, molecular biology, biochemistry, microscopy, etc. on fruit flies towards the study of neurodegenerative disease models. This position will be exclusively dedicated to the Undiagnosed Diseases Network. Required: PhD in biosciences or equivalent field
Post-Doctoral Research Position EmployerUT MD Anderson Dept Lymphoma/Myeloma LocationHouston, TX Application DeadlineOpen Until Filled Job Description This is a full-time, hands-on laboratory post-doctoral research position in the Department of Lymphoma/Myeloma. Applicants must have a recent Ph.D. and/or M.D. with focused research on the relevant subjects. The successful candidate will have a track record of productivity in research and have the talent and dedication to take advantage of the vast resources available at The University of Texas MD Anderson Cancer Center and the rest of the Texas Medical Center. The primary duties of this position will be devoted to the characterization of mechanisms used by cancer cells to regulate apoptosis (see Leukemia 2014;, 12:2376-87; J Hematol Oncol. 2015 Jun 6;8:63; PLoS One. 2015 Mar 4;10(3):e0117994; Mol Cancer Res. 2015 May;13(5):809-18; Blood 2011, 118:3107-3108; Lancet Oncol. 2014 Nov;15(12):1311-8). Prior training using molecular biology, cell biology, protein biochemistry, mammalian cell culture techniques and proficiency in scientific writing is mandatory; experience in gene profiling and bioinformatics is a definitive plus. MD Anderson Cancer Center provides a vast scientific environment to support research programs. Current laboratory projects involve molecular, biochemical, and cellular approaches for deciphering apoptosis signaling mechanisms. Mouse models with the relevant genetic lesions are available to substantiate these projects. Salary is commensurate with experience.
Postdoctoral Research Associate Employer: University of Pittsburgh Location: Pittsburgh, Pennsylvania Salary: The University of Pittsburgh offers competitive compensation and benefits packages. Job Type Postdoc, Postdoc Fellowship, Research Scientist The Department of Surgery, Division of Surgical Oncology at the University of Pittsburgh has immediate openings for talented and passionate postdoctoral research associates. The Division of Surgical Oncology’s primary goal is to develop novel methods for treating cancers through immunology, virology, and molecular biology techniques, and to translate research findings into patient treatments. We are interested in recruiting PhD or MD/PhDs candidates for laboratories that focus on 1) Viral therapies for cancer and 2) Cancer immunotherapies, specifically adoptive T cell therapies for cancer. Candidates that have an interest in mechanistic and translational studies in cancer biotherapies are encouraged to apply. The qualified applicants will be required to conduct research, interpret results, prepare manuscripts, and aid in the preparation of grant applications. The required expertise includes all common molecular biology and immunology techniques, molecular cloning, cell culture, and experience with murine in vivo models. The applicant should have command of the English language, good interpersonal skills, critical thinking ability and evidence of experience and good writing skills through first author publications in peer reviewed journals. The applicant should also be proficient in computer software usage including Word, Excel, PowerPoint, and statistical packages. To be considered for one of these positions, please provide a one-page statement of research interest, a current curriculum vitae and contact information for three-references.
Postdoctoral Fellow in Molecular & Cellular Biology and Biochemistry Employer: Johns Hopkins University Location: Baltimore, Maryland (US) Salary: salary commensurate with experience Job Type: Postdoc, Postdoc Fellowship, Research Scientist Highly motivated candidates are invited to lead several new projects to address fundamental questions in RNA and protein homeostasis related to neurodegenerative diseases. Current directions in the lab include novel functions of nucleic acids, RNA binding proteins, and protein quality control and translation. Experimental approaches, including biochemistry, genetics, and cell biology, from invertebrate to mammalian systems are employed. New techniques applied in the lab include iPSC neurons, genome editing, and metabolomics studies. Candidates with a strong background in biochemical, molecular, and/or cellular biology are encouraged to apply. The Johns Hopkins Medical Institutions provide a stimulating and collaborative environment for biomedical research. Our lab is affiliated with the Department of Biochemistry and Molecular Biology of the Bloomberg School of Public Health and the Department of Neuroscience of the School of Medicine. The Baltimore/Washington D.C. area also offers rich professional and living opportunities. Candidates should have a doctoral degree and strong research background. Please send a statement of research experience and career goals, a copy of Curriculum Vitae, and contact information of at least one reference.
Postdoctoral Fellow Employer: University of Illinois at Chicago Location: Chicago, Illinois Salary ~$45,000 per year + benefits Job Type: Postdoc, Postdoc Fellowship Description A position is available in the laboratory, for a highly motivated postdoctoral fellow to work in an interdisciplinary research environment at the interface between biomedical science and engineering. The postdoctoral fellow will work on integrative approaches to investigate how biophysical forces impact mesenchymal stem cell functions to modulate blood, lung and vascular systems. To both manipulate and measure physical forces exerted on cells, we use various microtechnologies, including micropipetting, atomic force microscopy, and microfluidics. These methods are used in combination with molecular biology and protein biochemistry to reveal mechanobiological insights behind force-dependent regulation of cell-cell communications. Fundamental insights from these efforts are aimed at developing multiscale biomaterial strategies for tissue regeneration by designing stem cell and organoid products ex vivo, controlling cell delivery in vivo, and targeting cells in situ. The Principal Investigator will help the applicant develop his/her career by providing a dynamic and collaborative research environment. The PI will encourage the preparation of research papers, application of fellowships, and presentation at national/international meetings. Environment The Department of Pharmacology at the College of Medicine (http://mcph.uic.edu) has a dynamic group of junior and senior faculty, research faculty, postdoctoral fellows and PhD students. The department's strengths are in the broad areas of cell signaling, cardiovascular and lung biology, stem cells and regenerative medicine, and drug discovery. The Department leads the field in funding and is home to a world-class graduate pharmacology program. In 2016, we were ranked 7th in the nation in our field in NIH research funding and in 2017, we were ranked in the top 11 in the United States based on QS World University Rankings by Subject in Pharmacy and Pharmacology. Duties The postdoctoral fellow is expected to develop and learn to utilize various techniques in both biological (e.g. molecular biology and protein biochemistry) and physical sciences (e.g. atomic force microscopy, micropipetting, biomaterial design, and microfabrication). To facilitate this effort, the fellow will have an access to various state-of-the-art facilities in the University of Illinois at Chicago campus , and other major institutions in the Chicago area through the Chicago Biomedical Consortium. Qualifications 1) Candidates must have a Ph.D. or M.D./Ph.D. degree. 2) Expertise in at least two of the following areas: Polymer chemistry to design biomaterials, including nanoparticles and hydrogels Fabrication and measurement at micro and nanoscales: e.g. microfluidics, microfabrication, micropipetting, and atomic force microscopy In vitro cell biology and engineering: e.g. primary cell isolation, FACS, 3D cell culture, confocal microscopy, and cell surface engineering In vivo animal studies (rodents): e.g. breeding, transplantation, survival surgery, and in vivo imaging 3) Minimum of two first-author primary research articles in international journals. 4) Excellent verbal and written communication skills in English.
Post-Doctoral Scientist Employer: George Washington University Location: Foggy Bottom Salary: $47,500 - $57,800 Job Type: Postdoc A postdoctoral research position is available immediately to study molecular mechanisms that enhance transcription and latency, and promote aging in human immunodeficiency virus (HIV) infected patients. You may also be required to conduct research with drugs of abuse and HIV/HCV co-infected human biological specimens. The responsibilities include: planning, conducting, analyzing experiments, preparing manuscripts, and presenting data through seminars and posters at scientific talks and meetings. The desired candidate must be willing to work with human peripheral blood, infected cell lines and human biological samples with viruses. The candidate should be experienced with molecular biology methods, mammalian tissue culture and transfections. Experience working with viruses and/or other human pathogens, prior experience with flow cytometry, ChIP assays and data analysis is desirable. Willingness to be trained to work with human biological samples (e.g. blood, tissue samples) is required. The applicant should have good command of English (speaking and writing). Additionally, if needed, should be ready to supervise undergraduate or graduate students and research assistants in conducting sample preparation and data analysis. Qualifications: A PhD in Biochemistry, Virology, Microbiology, Immunology, Genetics or related field is required. 1-2 years of research experience as postdoctoral level will be a plus. Publication history is desirable.
NIH-funded Postdoctoral Positions In the beautiful coast city of CHARLESTON, South Carolina Employer: Medical University of South Carolina/ Microbiology & Immunology Location: Charleston, South Carolina Salary: Salary commensurate with experience Posted April 25 2017 Three postdoc positions are available immediately in the laboratory of Dr. Li, Department of Microbiology & Immunology at the Medical University of South Carolina (MUSC). The purposes of these positions are to train independent investigators and to engage in NIH-funded projects whose goals are to: (1) define molecularly how TGFbeta signaling is controlled to impact on regulatory T cell biology and cancer immunotherapy; (2) understand the roles of platelets in cancer immune surveillance and develop novel combination therapy based on the mechanistic understandings; (3) disentangle the cross-talk among unfolded protein responses, microbiome, mucosal immunology and colon cancer. Dr. Li’s laboratory resides in the NCI-designated Hollings Cancer Center, which provides state of the art laboratory spaces as well as cutting-edge research core facilities including flow cytometry, mass cytometry, a cellular therapy facility, genomics, proteomics, multi-photon imaging, gene targeting/knockout and a translational research facility. Rich intellectual environment is ensured by more than twenty immunologists perusing their groundbreaking research in the immediate vicinity on immune tolerance, inflammation, transplantation immunology as well as cancer immunotherapy which is also supported by a new 5-year T32 training grant from NIAID. Successful candidates should hold a MD, PhD, MD/PhD or equivalent with a proven track record of scientific productivity in relevant topics indicated by first author publications of original research papers. Candidates with strong background with bioinformatics are also encouraged to apply. Charleston is a beautiful and historic Atlantic coastal town. This city offers the perfect mix of history, Atlantic coast beaches, food, art and music festivals and award-winning golf courses. Working at MUSC boasts the ideal combination of a rare opportunity to contribute to the growth of an already top-ranked medical institution while simultaneously enjoying the unsurpassed quality of life that this charming town has to offer.
Postdoctoral Fellow - Integrated Mathematical Oncology EmployerH. Lee Moffitt Cancer Center & Research Institute LocationTampa, FL Application DeadlineOpen Until Filled Job Description The Cancer Ecology and Evolution group led by Dr. David Basanta at the Integrated Mathematical Oncology department of the H. Lee Moffitt Cancer Center in Tampa, FL, is looking for a postdoctoral researcher to join the team. The Moffitt Cancer Center is one of the leading cancer centers in the nation and the only NCI-designated center in Florida, making it a unique place in which to develop blackboard-to-bedside treatments. Our group has been recently awarded an NCI grant to study the ecosystem of metastatic cancer in the bone so the prospective candidate should hold a PhD in a relevant field (mathematics, physics, computer science...) and have a very strong interest in cancer. We collaborate very closely with the lab led by Dr. Conor Lynch in the tumor biology department so the work we produce is highly integrative and requires the ability to communicate with experimentalist on a daily basis. The Department of Integrated Mathematical Oncology (IMO) consists of 7 internationally renowned cancer researchers and mathematical modelers. The focus of all IMO research groups is to apply physical, mathematical and mechanical principles to cancer biology to decipher first order principles of tumor growth that can be exploited for novel cancer treatments. Moffitt Cancer Center and Research Institute, in Tampa, is Florida's largest cancer center, located on the campus of the University of South Florida, near beautiful beaches in the Gulf of Mexico. Equal Employment Opportunity Moffitt Cancer Center is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, or protected veteran or disabled status. We seek candidates whose skills, and personal and professional experience, have prepared them to contribute to our commitment to diversity and excellence.
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