Our lab is focused on genomic imprinting, one of the most fascinating epigenetic phenomena. We have very broad research interests ranging from epigenetic regulation in stem cells and mouse embryos to modeling human diseases: diabetes, obesity, cancer, cardiovascular defects and neurological diseases.
Recently, we have discovered an important regulator in genomic imprinting (see Dev. Cell 15: 547-557, 2008 and Dev. Cell 15: 487-488, 2008). This gene Zfp57 is required for the acquisition and maintenance of DNA methylation genomic imprints. We are currently using both embryonic stem cells and mouse as model systems to investigate the essential roles of Zfp57 in epigenetic regulation, stem cell differentiation and embryonic development. These projects are currently funded by NIH and the State of New York. We are looking for motivated researchers with a PhD and/or MD degree in biomedical sciences to pursue independent research endeavors in highly competitive fields. Qualified candidates should have a strong research record with expertise in the areas of stem cells, epigenetics, developmental biology, molecular biology or biochemistry. Interested persons please send your CV and names of your referees to the following e-mail address: XL.MSSM@gmail.com.
The laboratory is located at Mount Sinai School of Medicine in Manhattan of New York City. Successful candidates will be eligible for subsidized university housing near the school and will have chances to interact with other labs in the Black Family Stem Cell Institute and Department of Developmental and Regenerative Biology to which my lab belongs.