英国癌症研究院-端粒生物学、癌症生物学方向博士后职位

英国癌症研究院-端粒生物学、癌症生物学方向博士后职位

Post-Doctoral Training Fellow - Telomere Biology

Cancer Biology, The Institute of Cancer Research

A postdoctoral research scientist position is available from March 2021 in the Telomere Biology Team at the Institute of Cancer Research, based in the heart of central London.

Telomeres allow eukaryotic cells to distinguish the ends of linear chromosomes from double strand breaks and protect them from repair processes and DNA damage. Telomere defects are observed in essentially all incidents of cancer and are thought to be a major driver of tumorigenesis. The Telomere Biology Team, led by Dr Max Douglas in the ICR Division of Cancer Biology, aims to understand how these fascinating structures are replicated and processed each cell division cycle, and how these steps are regulated in time and space.

We seek a postdoctoral research scientist to develop an innovative research project that will examine the molecular mechanism of telomere replication and processing steps. You will join an enthusiastic and collaborative group analysing DNA replication and the biology of telomeres using a multidisciplinary approach that employs reconstituted in vitro biochemical assays, structural biology and genetics (see for example Douglas et al, Nature 2018). You will be given opportunities to use your own initiative and to work in collaboration with others.

Applicants should possess a PhD in a biological science such as molecular cell biology, biochemistry or biophysics. Experience with in vitro biochemistry or structural biology is desirable but not essential.

Appointment will be on a Fixed Term Contract for 3 years in the first instance. The full salary scale for the post is in the range from £32,844 p.a. to £45,224 p.a. inclusive. Starting salary will be based on previous postdoctoral experience and is expected to be in the range of £32,844 (for pre-viva applicants) to £40,147 per annum.