美国加州大学伯克利分校基因组工程博士后职位

美国加州大学伯克利分校基因组工程博士后职位

Postdoctoral Scholar - Genome Engineering - Dept of BioEngineering

Job #JPF02554

College of Engineering – Bioengineering

Recruitment Period

Open date: March 26th, 2020

Next review date: Monday, Aug 31, 2020 at 11:59pm (Pacific Time) Apply by this date to ensure full consideration by the committee.

Final date: Monday, Aug 31, 2020 at 11:59pm (Pacific Time) Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.

DescriptionPostdoctoral Employee - The Hsu Lab

The Hsu Lab (https:// hsu.berkeley.edu) in the Department of Bioengineering (https:// bioeng.berkeley.edu) and Innovative Genomics Institute (https: // innovativegenomics.org/) at the University of California, Berkeley invites applications for a Postdoctoral Researcher position in the field of genome and protein engineering. Our research aims to understand and manipulate the genetic circuits that control brain and immune cell function to improve human health. We explore the rich biological diversity of nature to create new molecular technologies for genome and transcriptome engineering, perturb complex cellular processes at scale, and develop next-generation gene and cell therapies. To do this, our group draws from a palette of technologies including CRISPR-Cas, engineered viruses, genome sequencing, massively parallel reporter assays, and pooled genetic screens (Hsu Cell 2014, Tycko Molecular Cell 2016, Konermann Cell 2018, Zhang Cell 2018).

Appointment Length:

This is a full time position at 100% time for one year. The appointment may be renewed depending on availability of funding and satisfactory performance.

Duties of Position Included:

Will work in a team that is developing novel molecular technologies for genome engineering, therapeutics, and diagnostics. Some of the problems we are thinking about include new methods for genetic perturbations in high- throughput, editing of the postmitotic genome, therapeutic delivery at the neuro-immune interface. One major area of interest includes invention of genome editing modalities that bypass the need for endogenous DNA repair pathways, paving the way for more flexible gene therapies and functional genomics screens. Another effort involves a multi-laboratory collaboration to create sensitive CRISPR-assisted nucleic acid diagnostics for COVID-19. The successful candidate will have a strong interest in collaborative technology development, as this position involves multi-disciplinary work in molecular biology and protein biochemistry; cell biology; and genome biology/next- generation sequencing.

Minimum Basic Qualifications:

  Completion of all doctoral degree requirements except the dissertation at the time of application.Additional Qualifications (by start date):

  PhD degree or equivalent international degree

  The candidate may have no more than four years of post-degree research experience

Preferred Qualifications:

  Strong background in molecular biology, biochemistry, and genetics (or related discipline)

  Experience in molecular biology, protein biochemistry, library-based approaches, and next-generation sequencing methodologies is preferred. Bioinformatics programming skills (e.g. BASH, Python, or R) is desirable, but not required.

Salary

$53,460 - $61,800 full time annual rate, depending on experience.

Application Procedures

To apply go to: https: // aprecruit.berkeley.edu/JPF02554

Please direct all questions for this position to Patrick Hsu, pdhsu@berkeley.edu, with the subject line: Postdoc Position

This position will remain open until filled.

Reference Requirements:

Letters of reference will only be solicited for finalists.

All letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e., dossier service or career center), to the UC Berkeley statement of confidentiality (https:// apo.berkeley.edu/evalltr.html) prior to submitting their letters.