当前位置:知识人网 >> 国外博士后招聘 >> 正文内容

美国加州大学圣地亚哥分校招收博士后
文章来源:知识人网整理       更新时间:2020年06月30日

  美国加州大学圣地亚哥分校招收博士后

  We are recruiting postdoc scholars who love science and dare to invent

  We welcome bold minds who will innovate in the areas of RNA biology, spatial transcriptomics, single-cell technologies, the human protein interactome, small molecule-protein interactions, extracellular RNA, blood vessels and endothelial cells, or Diabetes research.

  About the PI

  Sheng Zhong is a Professor of Bioengineering at UC San Diego. He received an NIH Director’s Pioneer Award, an NIH Director’s New Innovator Award, an NSF CAREER Award, and an Alfred Sloan Fellowship. He is a fellow of American Institute for Medical and Biological Engineering (AIMBE). He leads the organizational hub of the NIH-funded 4D Nucleome Consortium. He also leads a Human Cell Atlas (HCA) seed network on single cell analysis of human blood vessels. Eight of his previous trainees are contributing to science on tenure-track faculty positions.

  About the lab

  Our lab invented the MARIO (Mapping RNA interactome in vivo) technology to massively reveal RNA-RNA interactions from human tissue (Nat Comm, 2016). We also invented the MARGI (Mapping RNA-Genome Interactions) technology for revealing thousands of chromatin-associated RNAs (caRNA) and their respective genomic interaction sites (Current Biology, 2017; Nature Protocols, 2019). Leveraging MARGI, we and our collaborators characterized caRNA’s roles in 3D organization of the nucleus (iScience 2018a), modulation of gene expression during progression of diabetes mellitus in blood vessel endothelium (bioRvix, 2019), and the biogenesis of fusion RNAs (PNAS 2019a).

  We contributed to discover that the earliest cell fate decision in mice is made sooner than the commonly thought 8-cell stage (Genome Res, 2014). Our Rainbow-seq technology combined tracing of cell division history and single-cell RNA sequencing into one experiment (iScience 2018b).

  We developed SILVER-seq for extracellular RNA (exRNA) sequencing from ultra-small volumes of liquid biopsy, solidifying a basis for future in vitro diagnostic trials using finger prick blood (PNAS, 2019b; Current Biology, 2020).

  We contributed to reveal that transposons are indispensable regulatory sequences in the mammalian genomes. Species-specific transposons are required for preimplantation embryonic development in humans and other mammals (Genome Res, 2010). Nature highlighted this discovery as ‘Hidden Differences’, reporting that ‘transposons or ’jumping genes’ had hopped in front of the genes, changing their regulation’ (Nature, 2010). We contributed to establishing the proof-of-principle that cis-regulatory sequences can be annotated by cross-species epigenomic comparison (Cell, 2012).

  Visit us at http://systemsbio.ucsd.edu. UCSD is an equal opportunity employer with a strong institutional commitment to excellence through diversity.



扫一扫知识人网官方微信订阅号,更多最新学术资讯、博士后招聘信息 一手掌握!国外博士后、访问学者申请免费专业评估,专家答疑解惑,一键关注离世界顶尖大学一步之遥!

快速申请国外博士后(免费评估)


点击这里快速申请国外博士后

点击这里快速申请国外访问学者

知识人网拥有10余年专职国外博士后、访问学者职位服务经验;
世界30000多所大学、研究机构职位机会,学术研究职位专业服务机构;
资深专业顾问将竭诚为博士精英们提供最优质的服务,实现您梦想的阶梯;
全国免费电话欢迎垂询:400-060-0581 直拨电话:010-68168664/68228237/68161776/68227792