美国凯斯西储大学神经退行性疾病研究博士后职位招聘

　　招聘简介：

　　博士后在神经退行性疾病研究中的地位

　　·凯西储备大学

　　·地点：俄亥俄州克利夫兰

　　·工作编号：7056496

　　·发布日期：2019年3月16日

　　职位描述

　　一个博士后职位立即可在凯斯西储大学医学院生理与生物物理学系的辛琦博士的实验室找到。

　　实验室主要研究线粒体病理学在神经退行性疾病发病机制中的作用。我们结合体外细胞培养、体内动物模型和病人源性神经元来研究神经退行性变的机制。实验室的另一个研究重点是开发治疗人类疾病的疗法。我们一直在使用合理设计的蛋白质-蛋白质相互作用的肽抑制剂和高通量筛选来鉴定神经疾病的治疗方法。

　　英文原文：

　　A postdoc position on studying neurodegenerative diseases

　　·         Case Western Reserve University

　　·         Location: Cleveland, OH

　　·         Job Number: 7056496

　　·         Posting Date: Mar 16, 2019

　　Job Description

　　A postdoc position is immediately available in the laboratory of Dr. Xin Qi in the department of Physiology & Biophysics at Case Western Reserve University School of Medicine.

　　The lab focuses on mitochondrial pathology in the pathogenesis of neurodegenerative diseases. We use a combination of in vitro cell culture, in vivo animal models and patient-derived neurons to study the mechanisms of neurodegeneration. Another research focus of the lab is the development of therapeutics for the treatment of human diseases. We have been using the rationally designed peptide inhibitors of protein-protein interactions and high throughput screening to identify therapeutics for neurological disorders.

　　The successful applicant will participate in projects on elucidating molecular basis of our novel transgenic mouse models of neurodegenerative diseases. The qualified candidate will also be part of our drug discovery project for neurodegenerative diseases. The applicant must have a PhD and/or MD degree in neuroscience, molecular biology, cell biology, pharmacology, or related field. Candidates with experience in neurodegenerative diseases and mouse models are highly desired.

　　Interested individuals should send a cover letter, CV, and the names/phone numbers of three people who could provide letters of reference by email to xxq38@case.edu.

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