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意大利罗马欧洲分子生物学实验室博士后职位
文章来源:知识人网整理       更新时间:2019年03月25日

  招聘简介:

  关于团队/工作

  Boulard和Gross团队正在寻找一位对表观基因组学和转录组学有浓厚兴趣的生物信息学博士后研究员,以领导对表观遗传学和神经科学接口项目框架中生成的大规模“OMIC”数据集的分析。

  本项目结合了Boulard和Gross两组在染色质生物学和神经回路方面的专业知识,分别探索转录因子和大脑表观基因组之间的细胞类型特异性相互作用。成功的申请者将加入一个由分子生物学家、生物化学家和神经科学家组成的合作团队。

  你的角色

  指定人员将负责大规模表观基因组和转录组数据集的计算分析,包括:

  1)开发分析Cutnrun和DAP Seq数据集的方法和管道,以及

  2)集成、比较、挖掘和可视化“OMIC”数据集。

  该职位涉及与湿实验室科学家合作开发和实施定制分析。

  英文原文:

  About the team/job

  The Boulard and Gross Groups are seeking to recruit a Postdoctoral Fellow in bioinformatics with a strong interest in epigenomics and transcriptomics to lead the analysis of large-scale “omic” datasets generated in the frame of a project at the interface of epigenetics and neuroscience.

  This project combines the expertise of the Boulard and Gross groups in chromatin biology and neural circuits, respectively, to explore the cell-type specific interplay between transcription factors and the brain epigenome. The successful applicant will be embedded in a collaborative team of molecular biologists, biochemists, and neuroscientists.

  Your role

  The person appointed will be responsible for the computational analyses of large-scale epigenomic and transcriptomic datasets, including:

  1) developing methods and pipelines to analyze CutnRun and DAP-seq data sets, and

  2) integrating, comparing, mining, and visualizing “omic” data sets.

  The position involves the development and the implementation of custom analyses in collaboration with wet-lab scientists.

  You have

  ·         PhD degree in Bioinformatics, Computer Science, Mathematics, or related fields.

  ·         Solid skillset and experience in bioinformatics:

  o    Excellent knowledge of R and biostatistics

  o    Experience and proven track record in handling NGS datasets and developing analysis pipelines

  ·         Outstanding interpersonal and communication skills are essential

  You might also have

  ·         Experience with Unix-based environment and high-performance computing cluster environment is not required, but would be considered an advantage.

  ·         Experience in motif discovery is not required, but would be considered an advantage.

  Why join us

  The European Molecular Biology Laboratory (EMBL) is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organization. The remuneration package comprises a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits. Please note that appointments on fixed term contracts can be renewed, depending on circumstances at the time of the review.

  What else do I need to know

  EMBL is one of the highest ranked scientific research organizations in the world. We are an international, innovative and interdisciplinary laboratory with more than 1600 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton, Hamburg, Grenoble and Rome. The Neurobiology and Epigenetics Unit at EMBL Rome studies mammalian physiology from the molecular to the systems level using the laboratory mouse as a model system. We take advantage of a full range of core facilities, including bioinformatics services and a high-performance computing cluster.

  For more information, please see our website at www.embl.it.

  To apply please submit a cover letter clearly stating your motivation and future research interests/plans and a CV with at least two referees through our online system at www.embl.it/jobs.

  Applications are welcome from all nationalities, appointment will be based on merit alone.

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