美国希望之城国家医疗中心生物钟对新陈代谢的调节研究博士后职位招聘

　　招聘简介：

　　博士后研究员-生物钟代谢调节

　　·希望之城

　　·地点：加利福尼亚州杜阿尔特

　　·工作编号：7056394

　　·发布日期：2019年3月11日

　　职位描述

　　关于希望之城

　　希望之城是一家创新的生物医学研究、治疗和教育机构，拥有6000多名员工，致力于预防和治疗癌症和其他危及生命的疾病，并以富有同情心、以患者为中心的理念为指导。

　　霍普市成立于1913年，总部位于加利福尼亚州杜阿尔特市，是一家卓越的非营利性机构，在这里同情和先进的护理与卓越的临床和科学研究紧密结合。希望之城是国家癌症研究所指定的综合癌症中心，也是国家综合癌症网络的创始成员，该网络是国家领先的癌症中心联盟，负责制定和制定癌症治疗的护理标准。

　　英文原文：

　　Postdoctoral Fellow - Circadian Clock Regulation of Metabolism

　　·         City of Hope

　　·         Location: Duarte, CA

　　·         Job Number: 7056394

　　·         Posting Date: Mar 11, 2019

　　Job Description

　　About City of Hope

　　City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

　　Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s leading cancer centers that develops and institutes standards of care for cancer treatment.

　　Position Summary

　　Two Postdoctoral Fellow positions are available in the laboratory of Dr. Ke Ma, Associate Professor, at the Diabetes and Metabolism Research Institute within Beckman Research Institute of City of Hope, CA. The Ma lab applies state-of-the-art circadian biology, molecular and cellular biology approaches to diabetes and obesity research, and we have established a unique program in deciphering the signaling mechanisms underlying circadian clock control in metabolic tissue development, growth and functional capacity. We are looking for highly motivated postdoctoral fellows with strong enthusiasm for metabolic disease or stem cell research to study molecular signaling pathways mediating circadian clock functions in adipose depots and skeletal muscle. Ultimately, our goal is to unravel circadian etiologies underlying the current epidemics of metabolic diseases for targeted therapeutic interventions.

　　Key Responsibilities include:

　　Utilizing biochemical and molecular biology approaches combined with animal physiology in genetic mouse models, the specific research directions in Ma Lab will explore:

　　epigenetic signaling networks mediating circadian clock nutrient-sensing function in adipose tissue and skeletal muscle;

　　circadian clock regulation of stem cell behavior in skeletal muscle development, growth, and regeneration; and

　　novel roles of circadian regulators in cancer development and metabolism.

　　Basic education, experience and skills required for consideration:

　　PhD in Molecular, Cellular or Developmental Biology;

　　Proficiency with biochemical techniques, molecular biology skills and cell culture systems;

　　Highly motivated with a proven track record of publications, and astrong interest in metabolic disease, epigenetics, or stem cell research;

　　Strong work ethic and ability to work effectively in a team.

　　Preferred education experience and skills:

　　Experience with in vivo animal model research;

　　Experience in biochemistry, gene regulation, with epigenetics and stem cell research and particularly genomic bioinformatics analysis;

　　Technical skills in metabolic, epigenetics, and stem cell research.

　　Additional Information:

　　For a list of lab publications, please click here.

　　For more information about Dr. Ma’s research, please click here.

　　Please include a brief research statement and list of three references with your application.

　　City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

　　City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.