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加拿大麦吉尔大学慢性疼痛和神经精神疾病方向博士后招聘

2019年03月12日
来源:知识人网整理
摘要:我们有兴趣研究慢性疼痛和神经精神疾病(脆性X综合征和孤独症)小鼠模型中转录和翻译水平的细胞类型特异性基因表达,并将基因表达的变化与结构可塑性、神经回路和动物行为的变化联系起来。我们使用先进的方法来分析基因表达(核糖体足迹,翻译核糖体亲和力纯化),以及生化、成像、电生理和行为分析。实验室里有几个令人兴奋的项目,由最近获得的CIHR资助。

  招聘简介:

  两个博士后职位可在麦吉尔大学的霍托尔斯基实验室获得。

  我们有兴趣研究慢性疼痛和神经精神疾病(脆性X综合征和孤独症)小鼠模型中转录和翻译水平的细胞类型特异性基因表达,并将基因表达的变化与结构可塑性、神经回路和动物行为的变化联系起来。我们使用先进的方法来分析基因表达(核糖体足迹,翻译核糖体亲和力纯化),以及生化、成像、电生理和行为分析。实验室里有几个令人兴奋的项目,由最近获得的CIHR资助。更多详情请访问:http://arkady-khootorsky.lab.mcgill.ca/

  麦吉尔大学提供了许多机会与疼痛和神经精神疾病领域的主要研究人员合作。蒙特利尔是一个充满活力、国际化、经济实惠的城市,拥有北美最强大的神经科学社区之一。

  鼓励有良好出版记录、积极性强、独立性强的个人申请。有膜片钳电生理学经验者优先。

  感兴趣的候选人应向arkady.khootorsky@mcgill.ca发送一封意向书、一份简历以及至少两名裁判员的姓名和联系方式。

  英文原文:

  Two postdoctoral positions are available in the Khoutorsky laboratory at McGill University.

  We are interested in studying cell-type-specific gene expression in mouse models of chronic pain and neuropsychiatric disorders (Fragile X syndrome and autism) at both transcriptional and translational levels and linking changes in gene expression to structural plasticity, alterations in neuronal circuitry and animal behaviour. We use advanced approaches to profile gene expression (ribosome footprinting, translating ribosome affinity purification), as well as biochemical, imaging, electrophysiological and behavioural analyses. Several exciting projects are available in the lab and are funded by recently awarded CIHR grants. More details can be found here: http://arkady-khoutorsky.lab.mcgill.ca/

  McGill University provides numerous opportunities to collaborate with leading researchers in the field of pain and neuropsychiatric disorders. Montreal is a vibrant, cosmopolitan, and affordable city with one of the strongest neuroscience communities in North America.

  Highly motivated and independent individuals with a solid publication record are encouraged to apply. Experience in patch-clamp electrophysiology is an advantage.

  Interested candidates should send a letter of interest, a CV, and names & contact information of at least two referees to arkady.khoutorsky@mcgill.ca.