比利时鲁汶肿瘤生物学中心癌症代谢/细胞信号学/分子生物学/免疫学方向博士后招聘

　　招聘简介：

　　我们（细胞代谢和代谢调节实验室; Fendt实验室）是一个年轻而充满活力的研究团队，致力于癌症转移和新型代谢途径的尖端癌症代谢研究。我们利用体内小鼠模型，代谢组学和13C示踪剂分析，获得对代谢作为癌症进展驱动力的突破性见解。我们的工作发表在高知名的期刊上，如Nature，Nature Communications，Cell Reports和Nature Immunology。我们在全球拥有强大的国际认可和顶级合作伙伴。

　　VIB-KULeuven癌症生物学中心（CCB）位于鲁汶大学的Gasthuisberg校区，有助于更好地理解癌症发生，进展和转移性传播的生物学，最终目标是开发更有效和更具体的抗癌（组合）疗法。建行目前由12个独立研究小组和单位的200多名科学家组成。我们的科学兴趣在于肿瘤的各种标志及其微环境，包括炎症，代谢，遗传和表观遗传调节回路。建行促进跨学科环境，并与位于同一校区的综合癌症中心LKI和大学医院密切合作，推动转化研究。

　　VIB是比利时法兰德斯的一家富有创业精神且充满活力的非营利性研究机构，专注于生命科学的开创性研究。来自60多个国家的约1500名科学家和技术人员在根特，鲁汶，安特卫普，布鲁塞尔和哈瑟尔特的5所弗拉芒大学工作，目前正在研究调节人体，植物和微生物功能的广泛分子机制。

　　英文原文：

　　Description

　　We (Laboratory for Cellular Metabolism and Metabolic Regulation; Fendt Lab) are a young and dynamic team of researchers performing cutting edge cancer metabolism research with special focus on cancer metastasis and novel metabolic pathways. We exploit in vivo mouse models, metabolomics and 13C tracer analysis to gain groundbreaking insights into metabolism as a driving force of cancer progression. Our work is published in high profile journals such as Nature, Nature Communications, Cell Reports, and Nature Immunology. We have a strong international recognition and top collaboration partners all over the world.

　　The VIB-KULeuven Center for Cancer Biology (CCB), located on the Campus Gasthuisberg of the University of Leuven, contributes to the better understanding of the biology that underlies cancer initiation, progression and metastatic dissemination with the ultimate goal to develop more effective and specific anti-cancer (combination) therapies. CCB is currently composed of more than 200 scientists in 12 independent research groups and units. Our scientific interest lies in various hallmarks of tumors and their microenvironment, including inflammation, metabolism, genetic and epigenetic regulating circuits. CCB fosters an interdisciplinary environment and close collaboration with the Comprehensive Cancer Center LKI and the University Hospital, both located on the same campus, to promote translational research.

　　VIB is an entrepreneurial and vibrant non-profit research institute in Flanders-Belgium with a clear focus on groundbreaking research in life sciences. About 1500 scientists and technologists from over 60 countries are based at the 5 Flemish Universities of Ghent, Leuven, Antwerp, Brussels and Hasselt, and are studying the broad spectrum of molecular mechanisms that regulate the functions of the human body, plants and microorganisms.

　　Profile

　　Are you interested in cancer metabolism and signaling pathways? You have a strong background (PhD) in cell signaling. You bring a strong expertise in dissecting signaling cascades (a background on mTOR is a plus), you have successfully applied state-of-the-art genetic engineering technologies (such as CRISPR/CAS9), and you are an expert in molecular biology techniques including but not limited to western blot, qPCR, FACS, immunohistochemistry (IHC), and cell culture techniques. Expertise in mouse models, cancer, the tumor microenvironment, and/or immunology is a plus. You are interested in metabolism research. You like taking the scientific and experimental lead on a challenging project. You can work independently but also like to collaborate within the team and other research groups. You aim for high impact.

　　We offer

　　o    Cutting edge research projects funded by the European Research Council (ERC)

　　o    The opportunity to lead exciting research projects in metastasis formation and novel metabolic pathways

　　o    Multidisciplinary and international collaborations

　　o    Beyond state-of-the-art technologies including mass spectrometry and single cell RNAseq

　　o    Team work and individual research career development

　　o    International team of young and dynamic researchers

　　Start date: June 2019

　　How to apply?

　　Please apply online: motivation letter, full CV, list of publications and contact details of 4 referees in one single pdf file

　　Deadline to apply: April 15, 2019.

　　For more information:

　　Please contact us (https://www.vibcancer.be/sarah-maria-fendt) or follow us on Twitter (@FendtLab)

　　About Leuven

　　Leuven - only 20 minutes away from Brussels by train - is a vivid university city with a rich history, a well-preserved historical town center and a lively multi-cultural atmosphere. The city is surrounded by charming small villages, woods and nature. Leuven has a lively atmosphere because of the many students from all over the world.

　　Leuven is home to KU Leuven, the largest and oldest university of the Low Countries and the one of the oldest universities in Europe. The related university hospital of UZ Leuven is one of the largest hospitals in Europe.

　　Leuven and the surroundings are a great place for young people and families to live and to raise children. There are many excellent day care centers and schools including an international school.