Postdoctoral fellow in immunotherapy of breast cancer : Boston, MA, United States

The Boston University-Boston Medical Center Cancer Center seeks a highly motivated postdoctoral fellow to investigate mechanisms of immune exhaustion and metabolism relevant to the immunotherapy of breast cancer. We are a highly dynamic, interdisciplinary, collaborative group of investigators focused on cancer disparities, and we have pioneered studies of BET bromodomain regulation in cancer and immunology. Research focuses on signal transduction of inflammatory cytokines and adipokines in the breast cancer microenvironment, and how they affect tumor cell aggressiveness and metastasis in cancer patients with co-morbid metabolic disease and immune exhaustion. We work in a safety net hospital setting.

Position summary

The successful candidate will work with leading academic clinicians and basic scientists, and conduct ground breaking research to elucidate understanding of the breast cancer microenvironment. The successful candidate will conduct pioneering work on the interplay of metabolism, tumor immune infiltrate and therapeutics in preclinical breast cancer models, with the ultimate goal of developing rational treatment hypotheses to be tested in the clinic. This research will deepen understanding of BET bromodomain mechanism and develop novel treatments (Cf: Andrieu & Denis, Mol. Cancer Res. 2018;16:580). The successful candidate will effectively communicate their work by presenting at national/international conferences and successfully publishing their results in premier journals.

Qualifications

Recent PhD or MD PhD graduate in cancer, immunology or related discipline.
Experience with molecular biology, biochemistry and cell biology, cancer immunology, metabolism, multiparameter flow cytometry, cell culture.
Experience in isolation and characterization of immune cells from primary human and mouse tissues.
Preferred familiarity with in vivo syngeneic mouse tumor models of breast cancer metastasis.
Demonstrated scientific rigor, scientific excellence and technical excellence.
Independent, highly self-motivated and innovative.
Proven track record in the field of immunology/tumor immunology and/or oncology, with relevant publications.
Excellent written and oral communication skills.
Willing to seek out grant funding from external sources in support of their independent research and may participate in writing grant proposals.
Outstanding interpersonal skills, strong work ethic and organizational skills.
Ability to excel in a goal-oriented, multifaceted and fast-moving team environment.

Boston University is an equal opportunity employer and gives consideration for employment to qualified applicants without regard to race, color, religion, sex, age, national origin, physical or mental disability, sexual orientation, gender identity, genetic information, military service, or veteran status or any other characteristic protected by law.

To apply for this position please send a cover letter and CV to Dr. Gerald V Denis, gdenis@bu.edu…

以上内容由知识人网博士后申请咨询老师整理发布，希望能给遇到此类状况的申请者们一个清晰的方向。想了解更多关于国外博士后、博士后招聘的相关资讯，可以登录我们的官方网站：www.zsr.cc。