贝勒医学院（BCM）癌基因组博士后招聘

Our lab focuses on studying the functional and clinical impact of poor prognosis tyrosine kinase mutations identified from cancer genome sequencing. We use a variety of preclinical models including cancer cell lines, Organoid cultures, patient-derived xenografts (PDXs), and Genetically engineered mouse models (GEMM). Drs. Kavuri and Matthew Ellis (Director of Breast center) lab made significant contributions on translating genome-sequencing findings into successful phase II clinical trials. (Bose. R and Kavuri. SM, Cancer Discovery, 2013; Kavuri. SM et al, Cancer Discovery, 2015; Ben-Baruch NE. et al, JNCCN, 2015; Ma. C et al, 2017, CCR; Huang. Kl.et al, Nature Communication, 2017). Our research is supported by Susan. G. Komen, CPRIT, and multiple Department of Defense grants (DOD). We are seeking highly motivated postdoctoral candidates, who are interested in translational solid tumor research.

Postdoc job description: The successful applicant must have PhD and/or MD and have strong skills with handling animal models including performing/maintaining therapeutic experiments using PDX models. Additionally, applicant must have hands on experience with genotyping of GEMM models. Bioinformatics skills will be advantageous. The applicant should have published in top tier journals and have successfully completed projects independently. Candidates who have recently complete or are about to complete their PhD will be considered. The candidates are expected to establish independent research projects and to generate high impact publications, which should provide the postdoctoral fellows with an excellent opportunity for further career development in academia.

Interested individuals should send a cover letter, CV, and the names/phone numbers of three people who could provide letters of reference by email to MeghaShyam.Kavuri@bcm.edu