李莫菲特H. Lee Moffitt 癌症研究中心肿瘤免疫学博士后招聘

Job Description

The Haura lab has an opening for a postdoctoral scholar in tumor immunology research. We pursue an interdisciplinary approach spanning immune biology and proteogenomics to characterize tumor immune states and response to immune therapy. We are looking for a highly motivated and independent postdoctoral research fellow who is interested in working on a project related to tumor neoantigens that predict response to tumor infiltrating lymphocytes and PD1 checkpoint therapy in lung cancer patients.

Position Highlights: 
This individual will design, conduct and interpret correlative experiments using human samples from accruing immunotherapy clinical trials, in particular a trial using adoptive cell transfer of tumor infiltrating lymphocytes (TIL). This individual will identify and validate predicted neoantigens from lung cancer immunotherapy trials using novel functional assays.The candidate will have immediate access to rich array of patient samples including frozen tumor and tumor cell suspensions, and apheresis products and will join a productive, energetic team of immunologists, bioinformaticians, clinicians, surgeons, and protein researchers within our group

The Ideal Candidate:
Successful candidates will have a publication track record demonstrating a strong background in in tumor immunology and/or immune-therapy; with an interest in translational research. Prior experience is required with some of the following techniques: high-throughput screening, mammalian cell culture, cell transfection assays, flow cytometry (FACS). Expertise in molecular biology (cloning, plasmid purification), and extraction of nucleic acids and protein from patient tissue samples is highly preferred. Candidates with experience in validating neoantigens in model systems will be given priority.

Responsibilities: 
Candidates with experience in cell culture, gene manipulation in cancer cells, cloning, T-cell activation assays or other immune cell based assays, and DNA/RNA/protein isolation techniques will be given preference.

Credentials and Qualifications: 
M.D. or PhD in Molecular Biology, Immunology, Biochemistry, or relevant field. 

Interested applicants should send their current CV with recent publications and contact information for three references to Dr. Eric Haura at Eric.Haura@moffitt.org

Moffitt Cancer Center is a premier cancer research institution in the United States. Built in an attractive location, it is the only NCI-designated cancer center in Florida and one of the top institutions in systems medicine and personalized cancer therapy. Moffitt features a number of high-quality core facilities equipped with state-of-the-art instrumentation and a cluster of expertise particularly in adoptive cell therapies.


H. Lee Moffitt Cancer Center & Research Institute is an equal opportunity, affirmative action employer, and a drug free workplace