Postdoctoral Fellow美国印第安纳大学分子遗传学方向博士后研究员

　　· Indiana University School of Medicine

 

　　· Location: Indianapolis, IN

 

　　· Job Number: 7051167

 

　　· Posting Date: Apr 23, 2018

 

　　· Application Deadline: Jun 22, 2018

 

　　Job Description

 

　　Position Announcement:

 

　　A postdoctoral fellowship is available in the Department of Medical and Molecular Genetics at the Indiana University School of Medicine (IUSM). This candidate will direct studies using in vitro and in vivo approaches for understanding the role of miR-29 in tumor-stromal biology of pancreatic cancer using miR-29 KO and genetically engineered pancreatic cancer animal models, biochemical and molecular genetics. In addition, the candidate will be involved in performing pre-clinical studies to evaluate the therapeutic use of miR-29 using gene therapy and pharmacological based approaches.

 

　　IUSM has dedicated pancreatic signature center with diverse basic and clinical expertise and excellent resources for pancreatic cancer research. In addition, IU Simon Cancer Center has state of the art research facilities and the Department of Medical & Molecular Genetics houses the viral vector production facility. This is creating an excellent environment for basic and transitional research.

 

　　The applicant should have the ability to work independently as well as in collaborative research projects. Duties and responsibilities are to perform experiments in a cancer biology research laboratory for in vivo characterization of mouse models, as well as cell culture experiments. Techniques include using transgenic and knockout mice for in vivo/ex vivo experiments, serum and tissue sample collection and analysis, cell culture, molecular cloning, generation of stable cell lines, CRISPR, RNA-Seq, IP/CLIP, transfection, qPCR, immunoblot, immunohistochemistry, and bioinformatics analysis.

 

　　Indiana University is an equal opportunity employer committed to building a diverse learning environment and on supporting the professional development of ethnic minorities, women, and people with disabilities. We strongly encourage applications from women and minorities.

 

　　Qualifications:

 

　　MD and/or PhD in Genetics, Molecular or Cell Biology, Biochemistry, or a related field. The candidate should be able to work independently, design and conduct experiments, and have effective oral and written communication skills. Prior experience or willingness to work with cancer animal (mouse) models is necessary. Experience or working knowledge in basic and advanced bioinformatics tools including TCGA data analysis is also highly desirable but not necessary.

 

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