Postdoctoral Research Assistant : Dundee, United Kingdom

Reference Number: SLSC0165
Job Title: Postdoctoral Research Assistant
School: Life Sciences
Unit: MRC Protein Phosphorylation and Ubiquitylation Unit
Grade: Grade 7, Spinal Points 29 – 31 only (£31,076-£32,958 per annum)
Job Category: Research
Closing Date: 7 October 2016

We are seeking a postdoctoral researcher to participate in the Division of Signal Transduction Therapy (DSTT) collaboration between the world’s major pharmaceutical companies (Boehringer Ingelheim, GlaxoSmithKline, and Merck-Serono) and the Ganley and Trost Labs at the MRC Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU). We are interested in characterising how neurodegenerative disorders such as Parkinson’s disease impact physiological transport pathways to the lysosome, with particular interest in autophagy, mitophagy and phagocytosis. We need a talented and highly motivated individual to develop and characterise novel state-of-the-art in vivo models (see McWilliams et al., JCB 2016 Aug 1;214(3):333-45) to visualise the in vivo role of key protein kinases in lysosomal trafficking.

MRC Protein Phosphorylation and Ubiquitylation Unit (PPU):

The successful applicant will have the opportunity to work in an exciting and collaborative research environment, equipped to the highest international standards. Major aims of the MRC-PPU are to advance understanding of the role of protein phosphorylation and ubiquitylation in cell regulation and human disease; to facilitate the development of drugs to treat diseases caused by abnormalities in phosphorylation; and to generate reagents and improve technologies. Another key remit of the MRC-PPU is to train the next generation of scientists who will advance our understanding in this crucial area of medical research. The MRC-PPU is in a beautiful location overlooking the estuary of the River Tay and embedded within the School of Life Sciences at the University of Dundee, which is one of the premier Life Sciences research Centres in the world.